Research Article
DAB2IP Stabilizes p27Kip1 via Suppressing PI3K/AKT Signaling in Clear Cell Renal Cell Carcinoma
Figure 1
DAB2IP is associated with decreased tumor size and better prognosis of ccRCC patients. (a) Association between DAB2IP mRNA level (RNA sequencing) and tumor size of ccRCC from TCGA. (b) Association between DAB2IP protein level (IHC) and tumor size of ccRCC. (c) Left, 50% cut-off point was used to dichotomize the DAB2IP mRNA level as low and high expression; right, Kaplan-Meier analysis (log-rank test) of the association between DAB2IP level and overall survival of ccRCC from TCGA. (d) Representative IHC staining of DAB2IP and p27 in ccRCC samples. (e) Pearson’s correlation analysis of DAB2IP and p27 protein levels in ccRCC.
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