Research Article
DAB2IP Stabilizes p27Kip1 via Suppressing PI3K/AKT Signaling in Clear Cell Renal Cell Carcinoma
Figure 7
AKT directly interacts with p27 in RCC cells. 786-0 KD cells transfected with WT or mutant (S10A) p27 constructs were subjected to IP assay. Myc-tag antibody was used to pulldown exogenous p27 proteins, and AKT antibody was used to detect the proteins binding to p27. indicates endogenous p27 proteins.