Computational and Mathematical Methods in Medicine

Research Article

[Retracted] Analysis of Efflux Pump System and Other Drug Resistance Related Gene Mutations in Tigecycline-Resistant Acinetobacter baumannii

Table 5

Base changes of non-synonymous mutations in adeRS, plsC, trm, and rpsJ genes of each strain and their corresponding amino acid changes.


Strain number	adeR	adeS	plsC	Trm	rpsJ

498	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val); GGC695GCC(Gly232Ala)	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion51A(CAA51CAG; Gln17Gln) 37 Stop	None

502	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val); GGC695GCC(Gly232Ala)	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion51A(CAA51CAG; Gln17Gln) 37 Stop	None

507	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val); GGC695GCC(Gly232Ala)	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None

511S	GAT58AAT(Asp20Asn); GTC358ATC(Val120Ile); GCA407GTA(Ala136Val); Insert652A(CTG652ACT; Leu218Thr) 229 Stop	CTC313TTC(Leu105Phe); CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	ATT88CAT(Asn30His); Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None

511R	GAT58AAT(Asp20Asn); GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	CTC313TTC(Leu105Phe); CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion51A(CAA51CAG; Gln17Gln) 37 Stop	None

512	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); CAG608CTG(Gln203Leu); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None

517	GAT58AAT(Asp20Asn); GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	CTC313TTC(Leu105Phe); CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Insert29A(GTG29GAT; Val10Asp) 16 Stop	None

524	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None

528	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	GCC281GTC(Ala94Val); CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion51A(CAA51CAG; Gln17Gln) 37 Stop	None

576	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val); Insert718G(CCC718GCC; Pro240Ala) 246 Stop	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile); ISAba1	ACT55CCT(Thr19Pro); CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None

579	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); AAA945AAT(Lys315Asn); GTT1042ATT(Val348Ile); ISAba1	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None

583	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	GCA289ACA(Ala97Thr); CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None

587	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); CGG584CAG(Arg195Gln); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile); ISAba1	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None

588	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	GCA289ACA(Ala97Thr); CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion51A(CAA51CAG; Gln17Gln) 37 Stop	None

590S	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GGC955AGC(Gly319Ser); GTT1042ATT(Val348Ile); ACC1048GCC(Thr350Ala)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None

591	GTC358ATC(Val120Ile); GCA407GTA(Ala136Val)	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GGC955AGC(Gly319Ser); GTT1042ATT(Val348Ile)	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	GAG135GAC(Glu45Asp); Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None

594	Insert32C(CAA32CCA; Gln11Pro) 13 Stop	CTT515CCT(Leu172Pro); GGT557GTT(Gly186Val); CGG584CAG(Arg195Gln); AAT802CAT(Asn268His); TAT908TTT(Tyr303Phe); GTT1042ATT(Val348Ile); ISAba1	CAA592AAA(Gln198Lys); TAA925AAA(Stop309Lys)	Deletion267A(ATA267ATG; Ile89Met) 92 Stop	None