Review Article
A Structured Review of Quantitative Models of the Pharmaceutical Supply Chain
Table 2
Quantitative models of pharmaceutical inventories.
| | Author | Source of uncertainty | Type of demand | Number of medicines | Constraints | Methodology | Objective |
| | Şatir and Cengiz (1987) | Demand | Stochastic | 3 | Budgetary
Shortage
Lead times | Stochastic optimization | Stock-out |
| | Vincent and Ranton (1984) | Demand | Stochastic | 1 | Space limitation
Delivery
Criticality | Optimization | Total costs |
| | Dellaert and Van De Poel (1996) | Demand | Stochastic | 1544 | | Optimization | Total costs |
| | Kelle et al. (2012) | Demand | Stochastic | 12 | Space limitation
Service level
Shortage | Optimization | Total costs |
| | Vila-Parrish et al. (2008) | Demand | Stochastic | 3 | Shelf life | Markov decision process
Simulation | Total costs |
| | Wu et al. (2015) | Demand | Stochastic | 1 | Space limitation | Simulation | Total costs |
| | Wang et al. (2015) | Demand | Stochastic | 1 | Shortage
Stock-out
Space limitation | Simulation
Heuristic | Total costs |
| | Çakici et al. (2011) | Demand | Stochastic | 1 | Lead times
Shortage | Stochastic optimization | Total costs |
| | Candan and Yazgan (2016) | | Deterministic | 15 | Space limitation | Optimization | Total net profit |
| | Guerrero et al. (2013) | Demand
Trigger an order
Delivery success | Stochastic | 4 | Space limitation
Service level
Quantity ordered | Markov decision process
Heuristic | Total costs |
| | Rappold et al. (2011) | Demand
Bill of material | Stochastic | 4 | Space limitation | Optimization | Total costs |
| | Bijvank and Vis (2012) | Demand | Stochastic | 1 | Space limitation
Service level | Heuristic | Service level
Capacity |
| | Little and Coughlan (2008) | Demand | Stochastic | 110 | Space limitation
Delivery
Criticality | Optimization | Minimum service level
Average service level |
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