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| Author | Source of uncertainty | Type of demand | Number of medicines | Constraints | Objective | Methodology | Supply chain components |
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| Kim (2005) | | Deterministic | | | Total costs | Optimization | Pharmaceutics Wholesalers Hospitals |
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| Baboli et al. (2011) | | Deterministic | 7 | Vehicle capacity Warehouse capacity | Total costs | Optimization | Warehouse Retailer |
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| Azzi et al. (2013) | | Deterministic | 3 | Warehouse capacity | Total costs | Optimization Simulation | Warehouse Hospitals |
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| Hassan et al. (2006) | | Deterministic | 8 | Warehouse capacity | Total costs | Multicriteria decision-making | Warehouse Hospitals |
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| Uthayakumar and Priyan (2013) | Lead times Demand | Stochastic | 3 | Lead times Payment delays Perishability Production rate | Total costs | Lagrangian relaxation | Warehouse Pharmacy |
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| Priyan and Uthayakumar (2014) | Total cost Lead times Demand | Stochastic | 3 | Lead times Payment delays Perishability Production rate | Total costs | Optimization | Warehouse Pharmacy |
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| Zhao et al. (2012) | Prices Demand | Stochastic | 1 | Production rate Budget | Profit | Heuristic | Manufacturer Distributor |
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| Nicholson et al. (2004) | Demand | Stochastic | 1 | Backorder Service level Warehouse capacity | Total costs | Heuristic | Manufacturer Warehouse Pharmacy |
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| Sinha and Matta (1991) | Demand | Stochastic | 1 | | Total costs | Optimization | Warehouse Pharmacy |
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| Rogers and Tsubakitani (1991) | Demand | Stochastic | 1 | Budget | Total costs | Lagrangian relaxation | Warehouse Pharmacy |
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| Balcázar-Camacho et al. (2016) | | Deterministic | 3 | Production rate Warehouse capacity | Total costs | Optimization | Manufacturer Warehouse Pharmacy |
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| Stecca et al. (2016) | | Deterministic | 4 | Production rate Warehouse capacity | Total costs | Optimization | Manufacturer Warehouse Pharmacy |
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| Dutta et al. (2007) | | Deterministic | 7 | Production rate Warehouse capacity | Total costs | Optimization | Manufacturer Warehouse |
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| Jetly et al. (2012) | Demand | Stochastic | 3 | Life cycle | Total costs | Simulation | Manufacturer Supplier Distributor |
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| Eberle et al. (2014) | Demand | Stochastic | 2 | Lead times | Total costs | Simulation | Manufacturer Warehouse |
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| Masoumi et al. (2012) | Prices Demand | Stochastic | 1 | Perishability | Product flows | Inequality theory | Pharmaceutics |
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| Hansen and Grunow (2015) | Demand Authorization | Stochastic | 1 | Production rate | Total costs | Stochastic optimization | Manufacturer |
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| Rego et al. (2014) | | Deterministic | 2 | Warehouse capacity | Total costs | Metaheuristic | Supplier Pharmacies |
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| Grunow et al. (2003) | | Deterministic | 5 | Lead times Production rate | Total costs | Optimization Heuristic | Manufacturer |
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| Amaro and Barbosa-Póvoa (2008) | | Deterministic | | Warehouse capacity Vehicle capacity | Total costs | Optimization | Supplier Pharmacies |
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| Weraikat et al. (2016) [63] | | Deterministic | | Warehouse capacity Vehicle capacity | Total costs | Optimization Lagrangian relaxation | Supplier Pharmacies |
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| Shih and Lin (2003) | | Deterministic | | Warehouse capacity Vehicle capacity | Total costs | Multi-criteria optimization | Supplier Pharmacies |
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| Weraikat et al. (2016) [65] | | Deterministic | | Warehouse capacity Vehicle capacity | Total costs | Optimization | Supplier Pharmacies |
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| Xie and Breen (2012) | | Deterministic | | Warehouse capacity Vehicle capacity | Waste | Optimization | Supplier Pharmacies |
|