Research Article

Joint Nonnegative Matrix Factorization Based on Sparse and Graph Laplacian Regularization for Clustering and Co-Differential Expression Genes Analysis

Table 3

Performance of different analysis methods.

 DatasetsiNMFiGMFNAjNMFiONMFSG-jNMF

AccuracyPAAD53.56 (0.00)63.44 (3.05)53.11 (0.01)56.23 (0.72)95.00 (0.00)
CHOL90.22 (1.71)97.33 (0.04)93.78 (0.49)90.04 (0.96)99.11 (0.00)
ESCA54.17 (0.00)54.58 (0.00)53.96 (0.00)58.70 (1.46)66.87 (0.01)
COAD61.87 (0.01)63.35 (0.02)59.15 (0.09)62.13 (0.22)68.84 (0.01)

RecallPAAD51.47 (4.68)58.07 (4.84)53.34 (4.50)48.44 (1.20)67.33 (2.26)
CHOL50.78 (2.01)56.17 (1.84)55.39 (2.04)46.41 (1.49)88.06 (0.47)
ESCA50.98 (0.29)51.31 (0.29)48.86 (0.27)51.13 (0.30)51.04 (0.12)
COAD49.34 (1.25)49.15 (1.30)49.65 (1.28)46.73 (1.08)56.18 (1.51)

PrecisionPAAD97.79 (0.05)98.60 (0.04)97.52 (0.05)97.71 (0.05)99.09 (0.01)
CHOL58.55 (0.20)62.21 (0.20)63.36 (0.21)60.54 (1.72)91.00 (0.10)
ESCA94.40 (0.05)95.20 (0.07)95.90 (0.08)95.67 (0.06)98.39 (0.02)
COAD49.34 (1.25)49.15 (1.30)49.65 (1.28)46.73 (1.08)56.18 (0.51)

F1-scorePAAD63.54 (3.70)66.70 (1.29)67.84 (1.71)64.42 (1.86)77.15 (2.12)
CHOL53.47 (2.01)58.19 (1.91)58.03 (2.04)51.61 (1.63)89.18 (1.04)
ESCA66.00 (0.18)66.47 (0.19)64.52 (0.18)66.41 (0.16)66.96 (0.16)
COAD63.71 (1.34)63.56 (1.27)64.25 (1.30)61.23 (1.14)71.11 (0.55)