Joint Nonnegative Matrix Factorization Based on Sparse and Graph Laplacian Regularization for Clustering and Co-Differential Expression Genes Analysis

Table 6

Co-DEGs identified by SG-jNMF of ESCA, CHOL, and COAD.

Genes	Related diseases	Relevance score with ESCA	Relevance score with CHOL	Relevance score with COAD
CHEK2	Prostate cancer and Li–Fraumeni syndrome 2	77.66	0.35	29.65
BRAF	Cardiofaciocutaneous syndrome 1 and lung cancer	55.71	13.44	67.81
RARB	Microphthalmia, syndromic 12 and chromosome 3P deletion	28.39	2.5	23.41
NFE2L2	Immunodeficiency, developmental delay, and hypohomocysteinemia and lung squamous cell carcinoma	25.81	2.54	28.18