Research Article
Study on Preparation Technology and Physical Fingerprint of Chuilian Jianpi Granules Based on QbD
Table 6
The physical evaluation index results of ten batches of granules (n = 10).
| | Batch number | Index | | Tap density | Bulk density | Hygroscopicity (%) | Water content (%) | Hausner ratio | Angle of repose (°C) | Relative homogeneity index |
| | 20201101 | 0.46 | 0.33 | 3.67 | 3.89 | 1.39 | 26.75 | 0.0096 | | 20201102 | 0.47 | 0.33 | 3.54 | 3.75 | 1.42 | 27.15 | 0.0098 | | 20201103 | 0.45 | 0.32 | 3.49 | 3.64 | 1.41 | 27.56 | 0.0102 | | 20201104 | 0.49 | 0.35 | 3.65 | 3.86 | 1.40 | 26.96 | 0.0101 | | 20201105 | 0.48 | 0.35 | 3.81 | 4.02 | 1.37 | 27.13 | 0.0096 | | 20201106 | 0.47 | 0.35 | 3.76 | 3.98 | 1.34 | 27.45 | 0.0102 | | 20201107 | 0.48 | 0.34 | 3.69 | 3.82 | 1.41 | 26.56 | 0.0095 | | 20201108 | 0.47 | 0.33 | 3.82 | 3.63 | 1.42 | 27.02 | 0.0096 | | 20201109 | 0.47 | 0.34 | 3.58 | 4.11 | 1.38 | 26.35 | 0.0101 | | 20201110 | 0.45 | 0.32 | 3.6 | 3.73 | 1.41 | 26.89 | 0.0097 | | Average value | 0.47 | 0.34 | 3.66 | 3.84 | 1.40 | 26.98 | 0.0098 |
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