Three Survival-Related Genes of Esophageal Squamous Cell Carcinoma Identified by Weighted Gene Coexpression Network Analysis

Table 1

Univariate and multivariable Cox regression analysis of prognosis factors in the training set for OS.

Variable	Univariate analysis			Multivariable analysis
	HR	95% CI	value	HR	95% CI	value
OS
Risk score (high vs. low)	5.319	1.576–17.951	0.007	6.815	1.840–25.248	0.004
TNM stage
(Stage II vs. I)	1.035	0.221–4.843	0.965	1.758	0.326–9.485	0.512
(Stage III vs. I)	1.927	0.404–9.188	0.410	3.254	0.581–18.216	0.179
(Stage IV vs. I)	3.929	0.626–24.640	0.144	10.372	1.345–79.977	0.025
Age (≥60 vs. <60 years)	1.321	0.585–2.983	0.503

Abbreviation. CI: confidence interval; HR: hazard ratio; OS: overall survival; TNM: tumor-node-metastasis; ; ; and .