Mechanisms of How Random Input Controls Bursting Gene Expression

Figure 6

The mean mRNA number (a, c) and expression noise (b, d) of downstream gene expression under the AM paradigm. (a, b) indicates that the upstream signal is an activator, while (c, d) indicates that the upstream signal is a repressor. The red line represents the upstream stimulus signal as noiseless, and the green line represents the upstream stimulus signal as random with the burst frequency () changing and the burst size () being equal to 2, while the blue line represents the upstream stimulus signal as also random with the burst frequency () being equal to 2 and the burst size () changing. The other parameters are the same as in Figure 2.

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(b)

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