A Case of Hepatotoxicity Induced by Therapeutic Ketamine Use for Sedation

Table 1

Trends of ketamine dose and laboratory values.

	Daily ketamine dose (mg)	Cumulative ketamine dose (mg)	Ketamine rate (max mg/hr)	AST (IU/L)	ALT (IU/L)	ALP (IU/L)	Bilirubin, total (mg/dL)
Day 1	64	64	5	28	11	88	0.4
Day 2	210	274	9	31	11	77	0.4
Day 3	346	620	19	27	11	75	0.3
Day 4	473	1093	24	29	12	76	0.2
Day 5	576	1669	24	—	—	—	—
Day 6	576	2245	24	30	14	73	0.3
Day 7	896	3141	47	21	13	72	0.3
Day 8	254	3396	24	24	15	77	0.3
Day 9	0	3396	0	59	36	94	0.4
Day 10	0	3396	0	44	41	91	0.3
Day 11	22	3417	24	28	37	90	0.4
Day 12	620	4037	47	26	34	107	0.4
Day 13	1240	5277	94	—	—	—	—
Day 14	2256	7533	94	33	38	109	0.4
Day 15 (AM)	1270	8803	94	160	114	166	0.5
Day 15 (PM)				211	226	270	0.5
Day 16	0	8803	12	141	198	252	0.5
Day 17	0	8803	0	42	112	208	0.5
Day 18	0	8803	0	23	70	178	0.5
Day 19	0	8803	0	14	45	148	0.6
Day 20	0	8803	0	14	31	123	0.6