Simultaneous Oral and Umbilical Locations as a First Sign of Pemphigus Vulgaris

Figure 5

Histopathological and IFD of the oral biopsy. The oral biopsy concerned a squamous mucosa lined with a partially visualized coating, with disappearance of the superficial layers and the presence of cells of the basal layer which remain attached to the underlying chorion, drawing a “tapestry nail” appearance, surmounted by a few acantholytic cells. In the chorion, we noted the presence of a polymorphic inflammatory infiltrate rich in eosinophilic polynuclear cells. Direct immunofluorescent examination was negative.