Isolated Bone Lesions in the Mandible and Maxilla of Langerhans Cell Histiocytosis Treated with Fractionated Stereotactic Low-Dose Radiotherapy: Case Report and 5-Year Follow-Up

<div>(a) Gingival ulcer proliferative growth in relation with the restored right maxillary molars. (b) 2D panoramic radiograph showing the unilocular radiolucency in the maxilla and the mandible. (1) Axial images of the CT scan exposed the presence of radiolucency in the maxilla with cortical bone deterioration. (d) axial images of the CT scan displaying a well-defined localized radiolucency in the body of the mandible. (e) The excised tissue after tooth extraction. (f) Histopathology of Langerhans cell histiocytosis: prominent histiocytes with abundant cytoplasm against the background of mixed population of eosinophils and multinucleated giant cells (HE ×10).</div>

Case Reports in Dentistry

fig1

Figure 1

Figure 1: Isolated Bone Lesions in the Mandible and Maxilla of Langerhans Cell Histiocytosis Treated with Fractionated Stereotactic Low-Dose Radiotherapy: Case Report and 5-Year Follow-Up 

Figure 1 | Isolated Bone Lesions in the Mandible and Maxilla of Langerhans Cell Histiocytosis Treated with Fractionated Stereotactic Low-Dose Radiotherapy: Case Report and 5-Year Follow-Up 