Orofacial Pain with Cardiac Origin of Coronary Artery Disease: A Case Report and Literature Review

Table 1

Summary of previous case reports.

Case number [ref], year	Age/sex	Craniofacial pain location (radiation)	Other pain symptoms (radiation)	Precipitating factors	Associated symptom	Medical history, family history	Cardiac treatment	Final diagnosis
1 [7], 1963	62/F	Bilateral Mn, neck, zygoma, temporal area	None	Unknown	Vomit,syncope	HTN	Death of arteriosclerotic heart disease	MI
2 [8], 1981	67/M	Bilateral Mn	None	(+): Walking back to work after lunch	Unknown	Unknown	Propranolol, nitrates	AP
3 [8], 1981	56/F	Bilateral anterior Mx, infraorbital	Neck, shoulder pain	No association with exertion	Dyspnea, orthopnea	Mild scleroderma	Aortocoronary bypass	AP, MI
4 [8], 1981	79/M	Bilateral Mn	Chest pain	(−): Isosorbide dinitrate	Unknown	Unknown	Unknown	MI
5 [48], 1998	56/M	Teeth, Mn	None	(−): Sublingual nitroglycerine	Unknown	Spinal cord injury	CABG	AP
6 [30], 2008	63/F	Left teeth	None	Unknown	Unknown	Grave’s disease, chronic depression	Unknown	Referred pain from vagus nerve
7 [49], 2011	48/M	Bilateral TMJ pain	None	Unknown	Unknown	Car accident	CABG	AP
8 [9], 2013	59/F	All teeth, bilateral Mn, Mx	None	(+): Walking,(−): Rest	Nausea	RA, OA, discoid lupus, HTN, IHD family history	Isosorbide mononitrate, statin	AP
9 [10], 1970	72/F	Right Mn	Chest pain on exertion	(+): Effort or stress	Unknown	Unknown	Unknown	AP
				(−): Rest and vasodilator
10 [11], 1975	32/M	Left Mx posterior teeth	Chest pain (shoulder, back pain)	(+): Physical activities	Unknown	None	CABG	AP, MI
				(−): Nitroglycerine
11 [12], 2005	50/F	Bilateral Mn, Mx, left temporal area	Chest pain (neck, arm pain)	(+): Exercise emotion	Unknown	DM, CABG	Unknown	AP
				(−): Relax
12 [13], 2006	65/F	Bilateral zygoma, (Mn and left temporal region)	Chest pain, arm pain (neck pain)	(+): Mandibular movement, walking, climbing stairs	Nausea, diaphoresis, vomiting	Thyroidectomy, MI	Propranolol, isosorbide dinitrate, aspirin	MI, AP
13 [14], 2006	61/F	Bilateral Mx, Mn (eye)	Chest pain	Unknown	Unknown	DM, HTN, smoking hypothyroidism	Stent in left coronary artery	AP
14 [50], 2010	80/M	The area of dental extraction (forehead and neck)	Chest pain	(+): Walking	Unknown	DM, HTN	Angioplasty of the circumflex artery with implantation of a sirolimus eluting stent	AP
15 [16], 2012	54/M	Third quadrant including teeth	Chest, neck, and shoulder pain	Unknown	Unknown	NSAIDs (neck and back pain), HTN, type II DM, smoking (15 cigarettes/day), moderate drinker	Medication	Unstable angina
16 [16], 2012	79/M	Left Mn	Left arm	Unknown	Unknown	Type II DM, left knee prosthesis	Unknown	IHD
17 [17], 2015	Late 50s/F	Left face and Mx	None	Percussion and palpation on periradicular area	Unknown	Unknown	Unknown	MI and IHD

Mn, mandible; Mx, maxilla; HTN, hypertension; DM, diabetes mellitus; RA, rheumatoid arthritis; OA, osteoarthritis; MI, myocardial infarction; AP, angina pectoralis; IHD, ischemic heart disease; Ref, reference; CABG, coronary artery bypass graft; (+), aggravating factor; (−), relieving factor.