Primary Cutaneous CD30+ Anaplastic Large T Cell Lymphoma in a Patient Treated with Cyclosporine for Actinic Reticuloid

Figure 1

Showing photodistributed erythema (a, b) and massively infiltrated papulous plaques on the face and neck (b) of a patient with actinic reticuloid. Skin biopsy taken from the cheek (c) showing acanthosis and a diffuse lymphocytic infiltrate in the entire dermis. There was no evident epidermotropism of the T cell dominant infiltrate leading to the diagnosis of pseudolymphoma (d). A biopsy taken from eczematous lesions on the trunk (b) showing acanthosis with focal parakeratosis, thickened collagen bundles (>>), and a sparse, mainly lymphocytic infiltrate with hyperchromatic cells (<) in the upper dermis (e). Together, the histologic picture and clinicopathological correlation matched the diagnosis of actinic reticuloid.