|
| Case | Patient | Colchicine therapy course | Was colchicine successful? |
|
| Lao-Ang et al. Unknown date [8] | 49-year-old female | Colchicine 0.5 mg/day: complete resolution after 6 weeks and no relapse at 6-month follow-up | Yes |
| Pavithran [9] | 40-year-old male | Colchicine 0.5 mg BID and then maintenance dose of 0.5 mg/day: complete resolution after one week. No relapses at maintenance dose | Yes |
| Present case | 67-year-old female | Colchicine 0.6 mg per day, adalimumab 40 mg every two weeks, triamcinolone 0.1% cream or augmented betamethasone 0.05% ointment twice daily as needed: improvement within 3 weeks with one flare which resolved with topical steroids. There was no improvement with adalimumab and topicals alone | Yes |
| Bedi [10] | 28-year-old female | Colchicine 0.6 mg BID: initial response but flare at 3 months | Yes, but recurrence reported |
| Teraki and Sugai [11] | 72-year-old female with mild IgA elevation | Colchicine, unknown dose: initial complete response but recurrence 1-2 months later | Yes, but recurrence reported |
| Stefanaki et al. [12] | 57-year-old male with palmoplantar pustular psoriasis (PPP) | Colchicine 0.5–1.5 mg/day: started when patient had PPP eruption, not SPD (although had a recent history of SPD previously controlled with dapsone). At 12 month follow-up after starting colchicine and discontinuing dapsone, patient did not have relapse of PPP or SPD | Unclear, may have prevented recurrence |
| Orton and George [13] | 40-year-old female | Colchicine 1 mg/day: no maintained response | No |
| Bonifati et al. [14] | 54-year-old female | Colchicine, unknown dose: only partial control | No |
| Ratnarathorn and Newman [15] | 45-year-old male with nodal marginal zone lymphoma | Colchicine 0.6 mg TID and fluocinonide ointment: worsening of SPD over the next 3 months. Colchicine was discontinued | No |
| Khachemoune and Blyumin [3] | 28-year-old male | Colchicine 0.6 mg/day with dapsone 50 mg/day for 3 months: no response and had side effects such as diarrhea and weight loss | No |
| Berk et al. [16] | 51-year-old male | Colchicine, unknown dose: no benefit | No |
| Berk et al. [16] | 61-year-old male | Colchicine, unknown dose: no benefit | No |
| Voigtländer et al. [17] | 79-year-old female | Colchicine, unknown dose: no benefit | No |
| Romagnuolo et al. [18] | 80-year-old female | Colchicine, unknown dose: unknown benefit, discontinued due to “severe” gastrointestinal side effects | No |
| Naretto et al. [19] | 37-year-old female with systemic lupus erythematosus | Colchicine, unknown dose: no benefit | No |
| Todd et al. [20] | 71-year-old male with monoclonal IgA gammopathy | Colchicine, unknown dose: no benefit | No |
| Brown et al. [21] | 78-year-old female with chronic lymphocytic leukemia | Colchicine 1.5 mg/day: no benefit | No |
| Guerin et al. [1] | 69-year-old female with monoclonal IgA gammopathy | Colchicine, unknown dose: no benefit | No |
| Ahmad and Ramsay [22] | 57-year-old female with pyoderma gangrenosum and IgA myeloma | Colchicine 0.5 mg/day: no benefit | No |
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