Temozolomide-Induced Shrinkage of Invasive Pituitary Adenoma in Patient with Nelson’s Syndrome: A Case Report and Review of the Literature

Figure 2

Ultrastructural features of sparsely granulated corticotroph adenoma (original magnification, 9700x). The cell has well developed Golgi complexes, dilated endoplasmic reticulum, and sparse, variable in shape and electron density secretory granules that measure 200 to 250 nm in diameter. Perinuclear bundles of cytokeratin filaments are absent.