Unstimulated Serum Thyroglobulin Levels after Thyroidectomy and Radioiodine Therapy for Intermediate-Risk Thyroid Cancer Are Not Always a Reliable Marker of Lymph Node Recurrence: Case Report and a Lesson for Clinicians

Figure 2

Histology after thyroidectomy showing a tall-cell variant of papillary thyroid carcinoma: papillary architecture neoplasm consisting of proliferation of elongated cells with a large eosinophilic cytoplasm, “ground glass” nuclei, and evident nuclear grooves and pseudoinclusions (haematoxylin-eosin stain, 40X, (a)). The tumour showed scattered thyroglobulin cytoplasmatic staining of different intensity (20X, (b)) and strong and diffuse CK19 cytoplasmatic staining (40X, (c)). Immunohistochemical staining was performed using specific antibodies by indirect biotin streptavidin 3, 3′-diaminobenzidine (DAB) system.

(a)

(b)

(c)