Development of Fulminant Type 1 Diabetes Mellitus in a Patient with DRESS Syndrome

Figure 2

Low-power microscopy images of the patient’s skin biopsy (40x and 100x) show interface dermatitis with focal spongiotic dermatitis. On the high-power image, (400x) there is vacuolar interface dermatitis (lymphocytes tagging along the dermoepidermal junction) and rare necrotic keratinocytes within the epidermis. The histopathologic changes are nonspecific but can be observed in drug eruption reactions.