Central Hyperthyroidism due to Thyroid-Stimulating Hormone-Secreting Pituitary Microadenoma in an Adolescent Boy: Case Report and Review of the Literature

Table 3

Summary of the 7 cases reported in the literature of pediatric TSH-secreting pituitary adenomas and the present case.

Presentation	Tumor size	Function	Complications	Remission through surgery	Reference
15-year-old boy with hyperthyroidism	30 × 30 × 30 mm	TSH/GH/FSH/LH-omas	Inferior and superior extension	No	[14]
11-year-old girl after adenomectomy	48 × 62 × 58 mm	TSH/FSH-omas	Suprasellar, right temporal lobe extension	No	[15]
13-year-old boy with hyperthyroidism	20 × 15 mm	Solitary TSH-oma	Suprasellar extension Intratumor hemorrhage; Diabetes insipidus Hypopituitarism; Postoperative bacterial meningitis	No	[16]
16-year-old boy with goiter and hypertension	17 × 15 mm	TSH/FSH-omas	Suprasellar extension	No	[17]
13-year-old girl asymptomatic	28 × 25 × 29 mm	Solitary TSH-oma	Intrasellar and suprasellar extension	Successful treatment with somatostatin analogs	[18]
8-year-old boy with hyperthyroidism	Macroadenoma	Solitary TSH-oma	Suprasellar and sphenoidal extension	Yes	[19]
13-year-old boy with hyperthyroidism	40 × 45 mm	TSH/GH-omas	Compressing the surrounding structures; Secondary adrenal insufficiency	No	[7]
15-year-old boy with hyperthyroidism	5 × 6 × 7 mm	Solitary TSH-oma	No	Yes	Present case