Simultaneous Coexistence of Thyrotropin-Prolactin-Secreting Adenoma and Papillary Thyroid Carcinoma

Table 2

Literature review of thyroid cancer with TSHoma.

Case	Age	Sex	Size of TC (mm)	Size of PA (mm)	IHC of PA	Therapies of TSHoma	Therapies of TC	Evolution of TSHoma	Evolution of TC	References (year of publication)
1	55	M	50	30	TSH	TS adenomectomy	Total thyroidectomy/iratherapy	Remission	Remission	[2] (1991)
2	37	F	20	10	TSH	Refusing treatment	Total thyroidectomy/iratherapy	NR	Remission	[3] (1998)
3	27	F	30	10	TSH	Octreotide/TS adenomectomy	Partial thyroidectomy	Remission	NR	[4] (2000)
4	45	F	20	15	TSH	Octreotide/TS adenomectomy	Total thyroidectomy	Remission	NR	[5] (2001)
5	47	F	8	4	TSH/PRL	TS adenomectomy	Total thyroidectomy/iratherapy	NR	Remission	[6] (2006)
6	50	M	17	3	TSH	Refusing treatment	Total thyroidectomy	Stability	Remission	[7] (2009)
7	57	F	8	26	TSH/GH	Octreotide	Total thyroidectomy/iratherapy	Remission	Remission	[8] (2010)
8	38	F	40	14	TSH/FSH	Octreotide/TS/radiosurgery	Total thyroidectomy/iratherapy	Stability	Remission	[9] (2013)
9	27	F	10	28	TSH	TS adenomectomy/lanreotide	Total thyroidectomy/iratherapy	Partial response	Remission	[9] (2013)
10	33	F	14	20	TSH/GH	TS adenomectomy/cabergoline	Total thyroidectomy/iratherapy	Remission	Remission	[10] (2014)
11	47	M	15	19	TSH	TS adenomectomy/lanreotide	Total thyroidectomy/iratherapy	Remission	Remission	[11] (2015)
12	46	M	12	7	TSH/GH	TS adenomectomy/lanreotide	Total thyroidectomy/iratherapy	Remission	Remission	[11] (2015)
13	42	M	40	12	TSH	TS adenomectomy	Total thyroidectomy/iratherapy	Remission	Remission	[11] (2015)
14	44	F	30	16	TSH/GH/FSH	Octreotide/TS adenomectomy	Total thyroidectomy/iratherapy	Remission	Remission	[12] (2017)
15	27	F	NR	NR	TSH	Surgical resection for nasopharyngeal tumor (ectopic TSHoma)	Total thyroidectomy/iratherapy	Remission	Remission	[13] (2017)
16	57	M	NR	30	TSH	Octreotide/TS adenomectomy	Partial thyroidectomy	Remission	Remission	[14] (2018)
Our case	50	F	10	12	TSH/PRL	TS adenomectomy/lanreotide/cabergoline	Total thyroidectomy/iratherapy	Remission	Remission	-(2021)

NR, not reported; TC, thyroid cancer; PA, pituitary adenoma; IHC, immunohistochemistry; TSH, thyrotropin; PRL, prolactin; GH, growth hormone; FSH, follicle-stimulating hormone; TS, transsphenoidal.