Pregnancy in a Transgender Male: A Case Report and Review of the Literature

Table 1

Gender-affirming therapy	Dosing Frequency	Advantages	Disadvantages
Intramuscular testosterone	Every 1 or 2 weeks	Better compliance than topical due to less frequent dosage	Fluctuating testosterone levels, injection complications
Subcutaneous testosterone	Bi-weekly or weekly	Better compliance than topical, with a shorter needle than IM forms	Fluctuating testosterone levels, not approved in USA
Testosterone gel	Daily	Ease of application, and less variation in testosterone levels	Slower masculinization than IM or SC, potential transfer with contact
Testosterone patch	Daily	Ease of application, and less variation in testosterone levels	Skin irritation, and lower testosterone levels than gel