Case Report

An Atypical Presentation of Childhood Paraganglioma with Seizures: A Case Report and Review of the Literature

Table 1

Case reports of PCC/PGL with seizures in children and young adults.

Authors/yearAge (years)GenderPresenting symptomsInitial working diagnosisInvestigations, management, and outcome

Leiba et al. /2003 [18]20MaleGeneralized seizures and comaFocal seizures with secondary generalisationCatecholamines and imaging confirmed the diagnosis of PCC. Had surgery with the resolution of seizures (1-year follow-up)
Wall et al. /2009 [19]8FemaleSlow-growing cervical mass and progressive epilepsyGrand mal epilepsySurgical resection of mass with histology confirming paraganglioma. Normal urine catecholamine levels. Resolution of epilepsy (13-year follow-up)
Chartan et al. /2011 [20]4MaleHeadaches and status epilepticusNot statedCatecholamines and imaging confirmed diagnosis of PCC, had surgery, and was discharged. No complications or recurrent hypertension
Anderson et al. /2012 [5]15FemaleSevere headache, vomiting, dizziness, blurred vision, and a tonic-clonic seizureNot statedBrain imaging showed haemorrhage, plasma noradrenaline was high, and MRI revealed a right adrenal PCC. Symptoms resolved and blood pressure normalised after resection of the tumour
Jung et al. /2012 [21]15MaleHypertension, cyclic headache, and vomiting for 10 years. Seizure 6 weeks before the surgeryNot statedSubcortical intracranial haemorrhage in the left frontal area. CT showed 2 masses in the left adrenal gland. Spent 1 day in ICU and discharged 10 days postsurgery with no noticeable complications and events