Behavioral Phenotype, Electroclinical Features, and Treatment Options in Twins with Lrp2 Candidate Variants (Donnay–Barrow/Foar Syndrome)

Table 1

Characteristic clinical features.

	Patient 1 (P.A.)	Patient 2 (P.S.)
Sex	F	F
Hypertelorism	++	++
Downslanting palpebral fissures	+	+
High myopia	−	−
Iris coloboma	−	−
Short nose	+	+
Posterior angulated ears	−	−
Sensorineural deafness	−	−
Diaphragmatic hernia	−	−
Exomphalos/cord hernia	−	−
Malrotation of bowel	−	−
Agenesis corpus callosum	+ (partial)	+ (partial)
Developmental delay	++	++
Autistic features	++	++
Seizures	−	++
Sleep disorder	−	++
Proteinuria	−/+	+