Case Report

Mitochondrial DNA Missense Mutations ChrMT: 8981A > G and ChrMT: 6268C > T Identified in a Caucasian Female with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Triggered by the Epstein–Barr Virus

Figure 3

Methylamine tungstate, negatively stained, whole-mount TEM analysis of mitochondria (mt) isolated from the patient’s plasma. Mitochondria with different shapes and sizes, ranging from ∼400 nm (Panel (a)) to over 1 µm (Panel (f)), were identified. Some mitochondria are attached to “vesicle-like” structures protruding from the membrane (∼100 nm in diameter), pointed by white arrows in Panels (a–c). Scale bar: 100 nm.