A Child as a Donor for Hematopoietic Stem Cell Transplantation: Bioethical Justification—A Case Study on Sickle Cell Disease

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Essential condition</td><td class="align_center">Availability of a matched sibling donor</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left" rowspan="10">Eligibility criteria</td><td class="align_center">Stroke</td></tr><tr><td class="align_center">Elevated transcranial Doppler velocity</td></tr><tr><td class="align_center">Venoocclusive episodes</td></tr><tr><td class="align_center">Pulmonary hypertension</td></tr><tr><td class="align_center">Tricuspid regurgitation jet velocity &gt; 2,5 ms</td></tr><tr><td class="align_center">Osteonecrosis and/or avascular necrosis</td></tr><tr><td class="align_center">Red cell alloimmunization</td></tr><tr><td class="align_center">Silent stroke especially with cognitive impairment</td></tr><tr><td class="align_center">Recurrent priapism</td></tr><tr><td class="align_center">Sickle nephropathy</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Eligibility criteria for hematopoietic stem cell transplantation (HSCT) in sickle cell disease (SCD) [<a href="/journals/crihem/2017/8394732/#B7">7</a>].

Case Reports in Hematology

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Table 1

Table 1: A Child as a Donor for Hematopoietic Stem Cell Transplantation: Bioethical Justification—A Case Study on Sickle Cell Disease 