Bone Marrow-Liver-Spleen Type of Large B-Cell Lymphoma Associated with Hemophagocytic Syndrome: A Rare Aggressive Extranodal Lymphoma

Figure 3

Histopathologic features. BM biopsy shows patchy interstitial infiltration of large, PAX5 positive lymphoma cells without sinusoidal (CD34 positive) involvement (400x) (a). By IHC, less than 30% of tumor cells are positive for CD10 (400x) (b) and more than 30% positive for MUM1 (400x) (c).

(a)

(b)

(c)