Pure Red Cell Aplasia with Del(20q) Sensitive for Immunosuppressive Treatment

Figure 1

Histopathological features of the bone marrow in PRCA. (a) The bone marrow core biopsy section shows a slightly hypocellular marrow with intact granulocytic and megakaryocytic cells but the absence of erythroid colonies (hematoxylin and eosin, scale bar: 200 μm). (b) Immunoperoxidase staining for hemoglobin A highlights only scattered positive cells (dark brown) with no colony formation (scale bar: 200 μm). Most of the brownish appearing cells represent iron-laden macrophages.

(a)

(b)