PML-RARA Fusion Transcripts Detectable 8 Months prior to Promyelocytic Blast Crisis in Chronic Myeloid Leukemia

Figure 2

Cytogenetic findings at the time of promyelocytic blast crisis. (a) Conventional karyotype demonstrating t(15;17) (black arrows) and t(9;22) (red arrows) translocations. (b) FISH probes positive for the PML-RARA fusion. (c) FISH probes positive for the BCR-ABL1 fusion (dual-color, dual-fusion probes).