NGS Analysis of Clonality and Minimal Residual Disease in a Patient with Concurrent Richter’s Transformation and CLL/SLL

<div>MRD after R-CHOP therapy. Clonal reads were detected at a low level in total DNA from bone marrow (BM) and peripheral blood (PB) and after R-CHOP therapy. The B-cell repertoire shows severe contraction in the peripheral blood after R-CHOP therapy. C: clonal and LQ: LymphoQuant.</div>

Case Reports in Hematology

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Figure 4: NGS Analysis of Clonality and Minimal Residual Disease in a Patient with Concurrent Richter’s Transformation and CLL/SLL 