Ibrutinib Plus R-ICE Induces Remission in Blastoid Variant Mantle Cell Lymphoma with CNS Relapse

Figure 2

(a) Pretreatment axial and sagittal T1 weighted fat saturated postcontrast images show abnormal enhancement along the dorsal aspect of the spinal cord at the level of L1 and L2, with abnormal enhancement along the cauda equina nerve roots. Findings are highly suspicious for leptomeningeal disease with a differential of infectious and inflammatory etiologies. (b). Post-treatment axial and sagittal T1 weighted fat saturated postcontrast images show markedly improved enhancement at the level of L1 and L2 and of the conus medullaris and cauda equina nerve roots, with very subtle minimal enhancement.

(a)

(b)