Case Report

An Unusual Presentation of Extracavitary Primary Effusion Lymphoma: Internal Jugular Vein Occlusion, Intractable Symptoms of Intracranial Hypertension, and Prolonged Remission after Highly Active Antiretroviral Therapy

Figure 3

(a) Neoplastic cells diffusely positive for MUM-1. (b) HHV8 immunohistochemical stain is diffusely positive in neoplastic cells, while (c) a subset of neoplastic cells are positive for Epstein Barr virus encoded RNA by in situ hybridization staining. (d, e) The neoplastic cells show strong lambda light chain restriction (e) compared to kappa (d) light chain by in situ hybridization staining. (f) The neoplastic cells demonstrate a high proliferation index (<90%) as measured by Ki67 immunohistochemical stain. All images at 400X magnification.
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