Case Report

Archived Cytogenetic Cell Pellets Used to Detect a BCR::ABL1 Driver Mutation Eight Years before Disease Presentation

Figure 1

Philadelphia chromosome formation. (a) G-banded metaphases were prepared from unstimulated bone marrow cultures showing the t(9;22)(q34;q11.2) (black arrows). (b) FISH analysis showing BCR::ABL1 fusion (yellow arrows) in both interphase and metaphase cells using a tri-color (aqua not shown) dual fusion translocation probe (Abbott Molecular).