Case Series
Anti-N-Methyl-D-Aspartate Encephalitis as Paraneoplastic Manifestation of Germ-Cells Tumours: A Cases Report and Literature Review
Table 1
Clinical and immunological features of patients with Anti-NMDAR encephalitis.
| ID | Sex, Age (y/o) | Clinical features | CSF | 1st brain MRI | Anti- NMDAR | Autoimmunity | Tumor pathology |
| P1 | F, 29 | Anterograde amnesia | Cell: 13 | Normal | (+) CSF and serum | ANA 1/160 | Mature ovarian cystic teratoma | Myoclonias | Prot: 0.48 | ENAS (-) | Auditory hallucinations | OB: Negative | |
| P2 | F, 27 | Anterograde amnesia Tonic-clonic seizure | Cell: 15 | Normal | (+) CSF and serum | ANA 1/640 | Immature Teratoma Stage IA | Prot: 0.03 | ENAS (+) | OB: Negative | Anti Ro (+) |
| P3 | F, 33 | Anterograde amnesia | Cell: 159 | Cortical hyperintensity in uncus and hippocampus | (+) CSF and serum | Negative | Mature ovarian cystic teratoma | Dyskinesia | Prot: 1.16 | Sialorrhea and tachycardia | OB: mirror pattern | Tonic seizure | |
| P4 | F, 27 | Anterograde amnesia | Cell: 158 | Normal | (+) CSF and serum | Negative | Mature ovarian cystic teratoma | Tonic seizure | Prot: 1.03 | Delusions | OB: Negative |
| P5 | F, 24 | Anterograde amnesia | Cell: 11 | Normal | (+) CSF and serum | Negative | Mature ovarian teratoma | Lability of blood pressure | Prot: 0.42 | Complex partial seizures | OB: Negative |
| P6 | F, 17 | Anterograde amnesia Dystonias | Cell: 17 | Normal | (+) CSF and serum | Negative | Bilateral mature ovarian cystic teratoma | Prot: 0.21 | OB: Negative |
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Cell: cells/mm3; Prot: g/L.
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