Case Report

Acute Kidney Injury Secondary to Rhabdomyolysis and COVID-19: A Case Report and Literature Review

Table 1

Summary of the reported cases.

DemographicsClinical PresentationComorbiditiesPertinent labsClinical course and outcome

Taxbro et al. [15]38-year-old male1 week of fever, myalgia, nausea, emesis, dry cough, dyspnea, and abdominal painType 2 diabetes
Gout
CRP: 145 mg/dL
Creatinine: 51 mmol/L
D-dimer: 0.19 mg/dL
No reported CK
Complete recovery after ICU admission requiring intubation
LOS: 23 days
Valente-Acosta et al. [16]71-year-old male1 week of dry coughing, mild dyspnoea and fever, and myalgia and arthralgia, predominantly in his legsBenign prostatic hyperplasiaCRP: 2.9 mg/dL
Creatinine: 1.68 mg/dL
LDH: 541 U/L
D-dimer: 983 ng/mL
CK peak: 8,720 U/L
Complete recovery after ICU admission requiring intubation
LOS: 16 days
Singh et al. [17]34-year-old maleFever, cough, dyspnea, and weaknessPrediabetes
Creatinine 0.89 mg\dl


CK peak: 5,454 U/L
Died in hospital
LOS: not reported
71-year-old maleFever, cough, and dyspneaHypertension
Schizophrenia
Seizures

Creatinine: 4.1 mg/dL


CK peak: 10,247 U/L
Died in hospital
LOS: not reported
88-year-old maleConfusionDiabetes
Hypertension

Creatinine: 2.25 mg/dL


CK peak: 2,628 U/L
Died in hospital
LOS: not reported
36-year-old maleFever, cough, and dyspneaNone
Creatinine: 1.03 mg/dL


CK peak: 5,531 U\L
Died in hospital
LOS: not reported
39-year-old maleMyalgias, fever, cough, and dyspneaHypertension
Creatinine: 3.8 mg/dL


CK peak: 4,330 U/L
Died in hospital
LOS: not reported

Husain et al. [18]38-year-old maleSever, cough, dyspnea, and myalgiaNot reportedCRP: 98.3 mg/dL
Creatinine: 1.5 mg/dL
LDH: 398 U/L

CK peak: 33,000 U/L
Complete recovery after ICU admission
LOS: 3 months
Chedid et al. [19]51-year-old male2 days of diffuse myalgias, dry cough, and mild chillsHypertension
Type 2 diabetes OSA
CKD II
CRP: 98.3 mg/dL
Creatinine: 2.48 mg/dL
LDH: 2150 U/L

CK peak: 464,000 U/L
Dialysis as outpatient
LOS: not reported
Singh et al. [20]67-year-old maleFever and dyspneaHypertension
Creatinine: 1.16 mg/dL
LDH: 459 U/L
D-dimer: 0.62 ng/mL
CK peak: 19,773 U/L
Died in hospital
LOS: 21 days
39-year-old maleFever, myalgia, dyspnea, and altered mental statusHypertensionCRP: 98.3 mg/dL
Creatinine: 3.8 mg/dL
LDH: 907 U/L
D-dimer: 1.92 ng/mL
CK: 4,330 U/L
Died in hospital
LOS: 1 day

Alejandro et al. [21]89-year-old maleDyspnea, fever, cough, and malaiseHypertension, coronary artery disease, and heart failure with preserved ejection fractionCreatinine: 2.0 mg/dL
LDH: 805 U/L

CK: 2,751 U/L
Complete recovery
LOS: 12 days
Pellegrini et al. [22]34-year-old male2 days of emesis, sore throat, nonproductive cough, and dyspneaNot reportedCRP: 3.3 mg/dL
Creatinine: 1.4 mg/dL
LDH: 854 U/L

CK: 73,922 U/L
Complete recovery
LOS: 8 days
Chong and Saha [23]37-year-old male2 days of dyspnea and fatigueNot reported
Creatinine: 5.0 mg/dL


CK peak: 35,000 U/L
Died in hospital
LOS: 12 day
Chan et al. [24]75-year-old female4 days of weakness and decrease in appetiteCoronary artery disease, hypertension, and GERD
Creatinine: 1.2 mg/dL


CK: 2,767 U/L
Complete recovery
LOS: not reported
71-year-old maleGeneralized weakness and leg twitchingHypertension, seizure, CKD, and overactive bladder
Creatinine: 5.6 mg/dL


CK: 1,859 U/L
Hospitalized as inpatient
LOS: undetermined

Chetram et al., 2021 (this manuscript)62-year-old male3-day history of general feeling of malaise, poor appetite, decreased urine output, and blood in his urineHypertension, type II diabetes, obesityCRP: 136.39 mg/L
Creatinine: 4.9 mg/dL

D-dimer: 2.01 mcg/dL
CK peak: 327,629 U/L
Complete recovery
LOS: 26 days