Progressive Multifocal Leukoencephalopathy in a Multiple Sclerosis Patient Diagnosed after Switching from Natalizumab to Fingolimod

Figure 6

Neuropathological findings. Histology revealed areas of focal demyelination as indicated by a loss of myelin basic protein (a) and proteolipid protein (b). Despite the presence of prominent CD8 dominated inflammatory infiltrates (c), SV40-positive cells (JCV-infected cells, (d)) could not be detected.

(a)

(b)

(c)

(d)