Cognitive Sequelae of Central-Variant Posterior Reversible Encephalopathy Syndrome (PRES)

Figure 1

Sequences of MRI brain including DWI, ADC, initial FLAIR, and FLAIR on follow-up imaging, from left to right. Initial MRI (first three columns on the left) noted symmetric subcortical and cortical FLAIR hyperintensity involving the bilateral cerebral hemispheres including extensive involvement of the thalami and basal ganglia, without contrast enhancement. DWI was isointense, lacking diffusion restriction, and ADC was hyperintense, consistent with vasogenic edema. FLAIR sequence on repeat MRI (fourth column from the left) noted significant interval improvement, with mild residual hyperintensity in the parieto-occipital white matter.