Amantadine as a Potential Treatment for Marchiafava–Bignami Disease: Case Reports and a Possible Mechanism

<div>An MRI of the brain with a diffusion-weighted imaging (DWI) sequence showing restricted diffusion in the genu and splenium of the corpus callosum. A T1-weighted sequence shows hypointensity in the genu and splenium with corresponding hyperintensity on T2-weighted and T2-weighted fluid-attenuated inversion recovery (T2-FLAIR) images T2 and FLAIR. There is no enhancement noted with gadolinium (not shown).</div>

Case Reports in Neurological Medicine

fig1

Figure 1

Figure 1: Amantadine as a Potential Treatment for Marchiafava–Bignami Disease: Case Reports and a Possible Mechanism 