Tracheal Chondrosarcoma: Systematic Review of Tumor Characteristics, Diagnosis, and Treatment Outcomes with Case Report
Table 1
Selected characteristics of 18 cases of tracheal chondrosarcoma.
Year
First author
Sex
Age
Symptoms
Symptom duration (months)
Location
Grade (1–3)
Extratracheal extension
Size (cm)
Calcification
Treatment
Number of recurrences
Follow-up (years)
1967
Daniels
M
73
D, C, W
7
Lower
2
NR
2.5
NR
(1) ER‡
5 (local)
AWD, 3.0
(2) ER
1973
Fallahnejad
F
48
D, C, W
16
Upper
NR
Present
4.0
None
R
0
NED, 5.0
1978
Weber
M
71
D, C, Ho
4
Middle
NR
Present
3.0
Present
R
0
NED, 5.0
1985
Slasky
M
58
D
24
Lower
2
Present
2.0
Present
R
0
NED, 2.5
1986
Arévalo
M
74
D, P
0.25
Upper
1
Present
2.0
Present
R
0
NED, 1.0
1988
Matsuo
M
72
D, He
7
Middle
1
Present
5.0
None
(1) IR‡
1
NED, 0.5
(2) LaR
(3) R
1990
Salminen
M
57
D, C
3
Lower
3
Present
2.3
None
IR
5 (local & distant)
DOD, 14
1994
Leach
M
72
D
36
Lower
3
Present
6.5
Present
R
NR
NR
1998
Farrell
M
87
D
12
Middle
2
Present
3.0
NR
(1)
2 (local)
AWD, 1.0
(2) ER
(3) Rad
1997
Kiriyama
M
54
D, W
1
Lower
1
NR
2.0
Present
LaDeb/R§
0
NED, 3.5
2003
Maish
M
78
D
3
Lower
1
Present
NR
None
LaDeb/R§
0
NED, 0.5
2008
Umezu
M
34
D, He, W
8
Upper
1
Present
2.5
Present
R
0
NED, 6.3
2009†
Wagnetz
M
34
D, C, W
18
Upper
2
None
2.0
Present
ER/R§
NR
NR
2010
Mendonça
M
72
D, W, O
12
Upper
1
Present
NR
Present
LaDeb/Rad§
0
NED, 7.0
2010†
de Almeida
M
35
D
NR
Upper
2
None
NR
Present
R
NR
NR
2016
Kutzner
M
61
D
2
Lower
1
None
2.2
Present
ER/R§
0
NED, 1.0
M, male; F, female; NR, not recorded; C, cough; D, dyspnea; W, wheeze; Ho, hoarse; P, pneumonia; He, hemoptysis; O, odynophagia; R, resection; ER, endoscopic resection; IR, incomplete resection; LaR, laser resection; LaDeb/R, laser debulking/resection; UNK, unknown; Rad, radiotherapy; NED, no evidence of disease; AWD, alive with disease; DOD, died of disease. resection. †Patient with Maffucci Syndrome. ‡Patient with recurrences treated in numerical order. §Patient symptomatically treated with laser debulking or with endoscopic resection prior to definitive treatment of resection or radiotherapy.
