Atypical Fragility Fractures due to Bony or Soft Tissue Phosphaturic Mesenchymal Tumors: A Report of Two Cases

Figure 6

Photomicrograph of the specimen from Case 2. The tumor is composed of spindled to epithelioid cells admixed with few giant cells, with regions of grungy calcification (solid arrow) and hyalinized matrix (double arrow), surrounded by a rim of bone (dashed arrow). The presence of regions with increased cellularity (double dashed arrow) and nuclear atypia are features that have been associated with a more aggressive tumor biology [4] (Hematoxylin and eosin, 4×).