Laryngeal Giant Cell Tumor: A Case Report and Review of the Literature

Table 1

Summary of reported cases of GCT of the larynx.

Case	Age	Sex	Location	Treatment	Follow-up
Wessely [4]	51	Male	Cricoid	RT
Federova [7]	35	Male	Thyroid	Partial laryngectomy + RT	NED 1 y
Wagemann [8]	40	Male	Cricothyroid	Laryngectomy + RT	NED 7 y
Perrino [9]	32	Male	Cricoid	Laryngofissure + RT	NED 0.25 y
Kaliteevskii and Korol'kova [10]	52	Male	Thyroid	Laryngectomy
Pohl [11]	50	Male	Thyroid	RT	NED 2 y
Kohn [12]	50	Male	Epiglottis	NA
Rudert [13]	53	Male	Thyroid	Partial laryngectomy	NED 8 y
Hall-Jones [14]	26	Male	Thyroid	Laryngectomy	NED 1.5 y
Goto and Nakashima [15]	47	Male	Thyroid	Partial laryngectomy
Kotarba and Niezabitowski [16]	60	Male	Epiglottis	Partial laryngectomy	NED 0.5 y
Ribari et al. [17]	35	Male	Cricoid	Laryngectomy + RT	NED 6 y
Kubo et al. [18]	40	Male	Cricoid	Laryngofissure + 5-Fluorouracil + RT
Tsybyme and Bogdanskaia [19]	34	Male	Thyroid	Laryngofissure + RT
Borghese et al. [20]	28	Male	Thyroid	Laryngofissure	NED 1.25 y
Badet et al. [21]	23	Female	NA	NA
Murrell and Lantz [22]	42	Male	Thyroid	Laryngectomy + neck dissection
Martin et al. [23]	23	Male	Thyroid	Partial laryngectomy	NED 5 y
Miyata et al. [24]	60	Male	Thyroid	Laryngectomy
Werner et al. [25]	35	Male	Thyroid	Laryngectomy	NED 7.5 y
Hinni [26]	31	Male	Thyroid	Partial laryngectomy	NED 3 y
Wieneke et al. [27]	44	Male	Thyroid	Laryngectomy	NED 0.6 y
Wieneke et al. [27]	57	Male	Cricoid	RT	NED 1.6 y
Wieneke et al. [27]	37	Male	Cricoid	Partial laryngectomy	NED 13.9 y
Wieneke et al. [27]	40	Male	Thyroid	Partial laryngectomy
Wieneke et al. [27]	53	Female	Thyroid	Partial laryngectomy	NED 16.9 y
Wieneke et al. [27]	62	Female	Thyroid	Laryngectomy	NED 24.9 y
Wieneke et al. [27]	26	Male	Thyroid	Laryngectomy	NED 1.5 y
Wieneke et al. [27]	37	Male	Thyroid	RT + cyclophosphamide	NED 19.4 y
Wong and Seikaly [28]	49	Male	Thyroid	Partial laryngectomy	NED 2.7 y
Nishimura et al. [29]	31	Male	Thyroid	Partial laryngectomy	NED 0.7 y
Coyas et al. [30]	67	Male	Vocal cord	Laryngofissure + RT	NED 1 y
Present case	59	Male	Thyroid	Laryngectomy	NED 2.5 y

NA: not available; NED: no evidence of disease; and RT: radiation therapy.