Clinical Controversy Surrounding the Differential Diagnosis of Branchiogenic Carcinoma

Figure 2

Crypt of the left palatine tonsil lined by squamous cell epithelium lining showing areas of dysplasia and progression (a) to infiltrative moderately differentiated keratinizing carcinoma in the form of solid coalescent aggregations with foci of keratinization and comedo necrosis neoplastic squamous cells with frank atypia (b). Immunohistochemically, the neoplastic cells were positive for p63 (c) and showed strong and diffuse positivity for p16 (d). Hematoxylin and eosin-stained slides of the left palatine tonsil (a–d) at x20 (b, c, and d) and x40 (a) magnification.

(a)

(b)

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(d)