Diagnostic and Treatment-Related Challenges in Sinonasal Teratocarcinosarcoma: A Report of Three Cases

Table 1

Patient characteristics.

Patient no	Sex	Age at diagnosis	Tumor localization	Staging at diagnosis	Treatment strategy	Recurrent disease	Time to recurrent disease (months)	Recurrent disease treatment	Follow-upduration (months)	Outcome
1	Male	56	Nasal cavity, right	T4bN0M0	CT + S	Leptomeningeal metastases	0	BSC	3	DOD
2	Male	70	Ethmoid sinus, left	T4bN0M0	S + RT	Locoregional; leptomeningeal metastases	15; 28	Radiotherapy; radiotherapy	32	DOD
3	Male	45	Nasal cavity, right	T3N2bM0	S + RT	Pulmonary metastases	5	BSC	6	DOD

Age at diagnosis determined on the date of histopathologic confirmation. Staged in accordance with the TNM 8^th edition; soft tissues; head and neck. Defined as time since initial treatment. Patient no. 2 first developed locoregional recurrent disease. Leptomeningeal metastases occurred at a later stage. CT = chemotherapy; S = surgery; RT = radiotherapy; BSC = best supportive care; DOD = death of disease.