Ciliary Functional Analysis in Chronic Rhinosinusitis with Polyps after Multimodal Intervention: Oral Corticosteroid, Functional Endoscopic Sinus Surgery, and Omalizumab Injection

Table 1

Results of ciliary function and SNOT-22 score across different treatment conditions in a patient presenting with CRSwNP.

	CBF (Hz)	CBP (percentage of normal beating)	SNOT-22
Sample #1 (preoperative)	16.78 ± 1.51	95.65	45
Sample #2 (postoperative)	14.25 ± 4.25	41.18	45
Sample #3 (1 month omalizumab)	13.60 ± 2.75	90	Not evaluated
Sample #4 (3 months omalizumab)	16.03 ± 1.72	100	13

The first sample was taken preoperatively, under oral corticosteroids. The second sample was taken postoperatively, under intranasal glucocorticosteroid. The third sample was taken after one month of omalizumab injections. The fourth sample was taken after 3 months of omalizumab injections. CBF (Hz) = ciliary beat frequency in hertz; CBP = ciliary beat pattern; SNOT-22 = 22-Item Sinonasal Outcome Test. Numerical values in CBF column are expressed as mean ± SD (standard deviation).