Thyroid-Like Follicular Carcinoma of the Kidney in a Young Patient with History of Pediatric Acute Lymphoblastic Leukemia
Figure 4
Histologic and immunophenotypic features of TLFCK. (a) Low power view of tumor demonstrated follicles of variably sized and shaped follicles filled with dense eosinophilic material. (b) Papillary-like structure extending into lumen of a macrofollicle. (c) High power view of microfollicular area. (d) Tumor extended to renal capsular surface (blue ink), with periodic-acid-Schiff (PAS) positive diastase resistant material identified within follicular lumens. (e) A focus of isolated tumor cells was located 1.8 mm from the main tumor. ((f)–(h)) Immunohistochemical staining of tumor cells showed reactivity for (f) CK7 and no reactivity for (g) TTF-1 or (h) thyroglobulin. Scale bars represent 100 μm.
