Metachronous Occurrence of Granular Cell Tumor in Breast Skin and Scalp: Diagnostic Challenging Differentiating Benign from Malignant and a Literature Review

Figure 1

(a) Subcutaneous mass of breast. (b) Minimal acanthosis and epidermal pseudoepitheliomatous hyperplasia (H&E, ×50). (c) Ill-defined tumoral lesion with infiltrative pattern (H&E, ×100). (d) Compact nests and sheets of polygonal tumor cells (H&E, ×200). (e) Tumor cells expressing S100 (×100). (f) Tumor cells expressing CD68 (×200). (g) Tumor cells weakly expressing p53 (×200). (h) Ki-67 proliferation expressing approximately 1%.

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