|
| Author | Age/gender | Clinical features | Radiographic features | History of tobacco | Histopathology | Presence of HPV | Diagnosis | Treatment and follow-up |
|
| Enriquez et al. [1] (1980) | 56/M | Painless mass with fistulous tract in right parotid and mandibular ramus region | Osteolytic lesion in right mandible | Present | Finger-like projections, hyperkeratosis, hyperplastic and dysplastic basal cells | HPV analysis not done | Verrucous carcinoma arising in odontogenic cyst | En bloc resection of ascending ramus |
|
| Pomatto et al. [2] (2001) | Young woman/F | Maxilla (lining of maxillary odontogenic cyst) recurrent abscesses | — | — | — | HPV negative | Verrucous carcinoma arising from a maxillary odontogenic cyst | No recurrence or metastasis after 8 months |
|
| Aldred et al. [3] (2002) | 13/F | Swelling on right maxillary alveolus between impacted canine & root of lateral incisor | Radiolucency between impacted canine and lateral incisor | — | Hyperplastic epithelium with verrucous proliferation, koilocytes. | HPV negative | Odontogenic cyst with verrucous proliferation | Enucleation. No recurrence |
|
| Ueeck et al. [4] (2007) | 46/M | Lesion in left posterior mandible | Radiolucency in left ramus extending till subcondylar region and coronoid process | Absent | Hyperplastic epithelium with verrucous proliferation, vacuolated cells | HPV analysis not done | Keratinizing odontogenic cyst with verrucous proliferation | Enucleation. Evidence of residual tumour after 7 months. Left segmental mandibulectomy with reconstruction plate and iliac crest bone graft. No recurrence in 27 months |
|
| Mohtasham et al. [5] (2008) | 58/M | Exophytic, polypoid lesion on labial and palatal aspect of right anterior maxilla | Well-defined radiolucency | Absent | Finger-like projections, bulbous, thickened, downward growth of rete ridges with mild atypia and parakeratin plugging | HPV analysis not done | Intraosseous verrucous carcinoma originating in odontogenic cyst | Enucleation. No evidence of recurrence/metastasis after 2 years of follow-up |
|
| Dalirsani et al. [6] (2015) | 49/M | Left mandibular alveolar area | | — | Cauliflower like projection of epithelium along with neoplastic proliferation of odontogenic epithelium | HPV analysis not done | Verrucous carcinoma in addition to cystic ameloblastoma | Excision with preservation of rim of the inferior border. Iliac crest bone graft done to repair defects. No evidence of recurrence in 2 years of follow-up |
|
| Peng et al. [7] (2015) | 74/M | Left mandible Swelling and recurrent pus discharge | Impacted 34 and a large well-defined, radiolucent lesion surrounding the crown of 34. | Present | Hyperparakeratotic stratified squamous cyst lining epithelium and downgrowth of broad and bulbous epithelial ridges with pushing-border invasion into the fibrous cystic wall | HPV analysis not done | Intraosseous verrucous carcinoma arising from an infected odontogenic cyst | Surgical excision with 5 months of follow-up. No recurrence or metastasis |
|
| Kamarthi et al. [8] | 64/M | Painful swelling in left maxillary alveolus | Unilocular, radiolucent lesion extending from 21 to 25 | Present | Hyperplasia and verrucous proliferation in an odontogenic cystic lining | HPV analysis not done | Intraosseous verrucous carcinoma arising from an orthokeratinised odontogenic keratocyst | Enucleation of the cystic lining. No signs of recurrence after 6 months of recall visit |
|
| Present case | 13/M | Smooth, firm swelling in left posterior maxilla, in relation to impacted 26, 27 | Well-defined radiolucency around impacted 26 and 27 | Absent | Hyperplastic epithelium, parakeratin whorls, koilocytes, melanin pigmentation | HPV positive | Infected odontogenic cyst with verrucous proliferation exhibiting melanin pigmentation | Enucleation. Recurrence of the lesion (thrice) and death in 2-year follow-up period |
|
