Case Report

Neurotrophic Receptor Tyrosine Kinase 2 (NTRK2) Alterations in Low-Grade Gliomas: Report of a Novel Gene Fusion Partner in a Pilocytic Astrocytoma and Review of the Literature

Table 1

Summary of reported NTRK2 gene fusion alterations in low-grade neuroepithelial tumors. PA = pilocytic astrocytoma; GG = ganglioglioma; DNT = dysembryoplastic neuroepithelial tumor; LGG-NOS = low-grade glioma not otherwise specified.

5 fusion gene3 fusion geneNumber of casesHistologyReference

QKINTRK22PAJones DT, 2013
NACC2NTRK21PAJones DT, 2013
KANK1NTRK21PALopez GY, 2019
PMLNTRK21PACurrent patient
SLMAPNTRK21GGQaddoumi I, 2016
TLE4NTRK21GGPrabhkaran N, 2018
NAV1NTRK21DNTQaddoumi I, 2016
QKINTRK21LGG-NOSSolomon JP, 2019
BCRNTRK21Diffuse LGG-NOSJones KA, 2019