Epithelioid Malignant Peripheral Nerve Sheath Tumor in the Liver: Report of a Rare Unusual Case with Rhabdoid Morphology and Review of the Literature

Table 1

Histopathologic comparison of MPNST and EMPNST.

	MPNST	EMPNST
Morphology:	Spindle cell predominate	Epithelioid cell predominant
Immunohistochemistry:
SOX10	Patchy positive	Diffusely positive
S100	Negative to scattered positivity	Diffusely positive
H3K27me3	Lost in 50%	Retained
SMARCB1/INI1	Retained	Lost in 50-70%
Inactivating mutations:
SMARCB1/INI1	Absent	Present in 75%
NF1	Frequent	Occasionally present
NF2	Rare	Occasionally present
CDKN2A	Frequent	Occasionally present
TP53	Frequent	Occasionally present
SUZ12 and EED	Frequent	Absent

Abbreviations: MPNST: malignant peripheral nerve sheath tumor; EMPNST: epithelioid malignant peripheral nerve sheath tumor.