COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory Syndrome

Table 1

Investigations before and during COVID-19 course of illness.

Tests	Reference range	Before COVID-19	COVID-19 suspected	COVID-19 identified	During COVID-19 course
CBC
Hemoglobin	10.5–14.0 g/dL	10.7	9.4	7.7	9.7
WBCs	5–15 × 10^3 µL	16.6	9.6	31.6	86.1
Lymphocytes	15–80% of WBC count	12.7%	8.9%	5.4%	2.0%
Platelets	150–400 × 10^3 µL	474	270	529	811
Biochemistry
Creatinine	55–110 µmol/l	12	6	11	6
LDH	135–225 U/L	—	353	363	464
Coagulation
INR	1-2	1.02	0.88	1.1	1.15
PT	11–14 sec	13.8	12	14.8	15.4
PTT	30–40 sec	37.5	31	26.3	22.9
D-dimer	0–0.55 µg/ml	—	1.5	1.3	1.5
Inflammatory markers
CRP	0–5 mg/L	19.8	37.2	318	219.7
ESR	0–10 mm/hr	123	126	280	150
Ferritin	13–400 ng/ml	—	917	1732	2000
Cultures
Viral panel	—	Negative	Negative	Negative	Negative
COVID-19	—	—	Negative	Positive	Positive

CBC, complete blood count; CRP, C-reactive protein; COVID-19, coronavirus disease-2019; ESR, erythrocyte sedimentation rate; INR, International Normalized Ratio; LDH, lactate dehydrogenase; PT, prothrombin time; PTT, partial thromboplastin time; WBC, total white blood cells.